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DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients

Copy number alterations (CNAs) are crucial for colorectal cancer (CRC) development. In this study, DEAD box polypeptide 27 (DDX27) was identified to be highly amplified in both TCGA CRC (474/615) and primary CRC (47/103), which was positively correlated with its mRNA overexpression. High DDX27 mRNA...

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Detalles Bibliográficos
Autores principales: Tang, Jieting, Chen, Huarong, Wong, Chi-Chun, Liu, Dabin, Li, Tong, Wang, Xiaohong, Ji, Jiafu, Sung, Joseph JY, Fang, Jing-Yuan, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978808/
https://www.ncbi.nlm.nih.gov/pubmed/29535419
http://dx.doi.org/10.1038/s41388-018-0196-1