Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations

Recent evidence indicates synaptic dysfunction as an early mechanism affected in neuroinflammatory diseases, such as multiple sclerosis, which are characterized by chronic microglia activation. However, the mode(s) of action of reactive microglia in causing synaptic defects are not fully understood....

Descripción completa

Detalles Bibliográficos
Autores principales: Prada, Ilaria, Gabrielli, Martina, Turola, Elena, Iorio, Alessia, D’Arrigo, Giulia, Parolisi, Roberta, De Luca, Mariacristina, Pacifici, Marco, Bastoni, Mattia, Lombardi, Marta, Legname, Giuseppe, Cojoc, Dan, Buffo, Annalisa, Furlan, Roberto, Peruzzi, Francesca, Verderio, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978931/
https://www.ncbi.nlm.nih.gov/pubmed/29302779
http://dx.doi.org/10.1007/s00401-017-1803-x

Ejemplares similares

Ejemplares similares