Tissue Engineering: A Modular Strategy to Engineer Complex Tissues and Organs (Adv. Sci. 5/2018)

In article number https://doi.org/10.1002/advs.201700402, Eben Alsberg and co‐workers report the engineering of tri‐tissue tracheas using a scaffold‐free approach that allows for the integration of structural cartilage rings, prevascular blood vessel networks, and epithelial cells into a single cons...

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Detalles Bibliográficos
Autores principales: Dikina, Anna D., Alt, Daniel S., Herberg, Samuel, McMillan, Alexandra, Strobel, Hannah A., Zheng, Zijie, Cao, Meng, Lai, Bradley P., Jeon, Oju, Petsinger, Victoria Ivy, Cotton, Calvin U., Rolle, Marsha W., Alsberg, Eben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978967/
http://dx.doi.org/10.1002/advs.201870028
Descripción
Sumario:In article number https://doi.org/10.1002/advs.201700402, Eben Alsberg and co‐workers report the engineering of tri‐tissue tracheas using a scaffold‐free approach that allows for the integration of structural cartilage rings, prevascular blood vessel networks, and epithelial cells into a single construct. Neotracheas of various dimensions, including human size, are formed via cellular self‐assembly. Prevascular tracheas are subcutaneously implanted into mice and demonstrate anastamosis with and perfusion by host vasculature. [Image: see text]

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