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Stepwise occlusion of the carotid arteries of the rat: MRI assessment of the effect of donepezil and hypoperfusion-induced brain atrophy and white matter microstructural changes

Bilateral common carotid artery occlusion (BCCAo) in the rat is a widely used animal model of vascular dementia and a valuable tool for preclinical pharmacological drug testing, although the varying degrees of acute focal ischemic lesions it induces could interfere with its translational value. Rece...

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Detalles Bibliográficos
Autores principales:	Nyitrai, Gabriella, Spisák, Tamás, Spisák, Zsófia, Gajári, Dávid, Diószegi, Pálma, Kincses, Tamás Zsigmond, Czurkó, András
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979036/ https://www.ncbi.nlm.nih.gov/pubmed/29851990 http://dx.doi.org/10.1371/journal.pone.0198265

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