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An SCF(FBXO28) E3 Ligase Protects Pancreatic β-Cells from Apoptosis

Loss of pancreatic β-cell function and/or mass is a central hallmark of all forms of diabetes but its molecular basis is incompletely understood. β-cell apoptosis contributes to the reduced β-cell mass in diabetes. Therefore, the identification of important signaling molecules that promote β-cell su...

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Detalles Bibliográficos
Autores principales: Gorrepati, Kanaka Durga Devi, He, Wei, Lupse, Blaz, Yuan, Ting, Maedler, Kathrin, Ardestani, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979299/
https://www.ncbi.nlm.nih.gov/pubmed/29587369
http://dx.doi.org/10.3390/ijms19040975