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An SCF(FBXO28) E3 Ligase Protects Pancreatic β-Cells from Apoptosis
Loss of pancreatic β-cell function and/or mass is a central hallmark of all forms of diabetes but its molecular basis is incompletely understood. β-cell apoptosis contributes to the reduced β-cell mass in diabetes. Therefore, the identification of important signaling molecules that promote β-cell su...
Autores principales: | Gorrepati, Kanaka Durga Devi, He, Wei, Lupse, Blaz, Yuan, Ting, Maedler, Kathrin, Ardestani, Amin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979299/ https://www.ncbi.nlm.nih.gov/pubmed/29587369 http://dx.doi.org/10.3390/ijms19040975 |
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