Cargando…

MicroRNA Expression Analysis of In Vitro Dedifferentiated Human Pancreatic Islet Cells Reveals the Activation of the Pluripotency-Related MicroRNA Cluster miR-302s

β-cell dedifferentiation has been recently suggested as an additional mechanism contributing to type-1 and to type-2 diabetes pathogenesis. Moreover, several studies demonstrated that in vitro culture of native human pancreatic islets derived from non-diabetic donors resulted in the generation of an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sebastiani, Guido, Grieco, Giuseppina Emanuela, Brusco, Noemi, Ventriglia, Giuliana, Formichi, Caterina, Marselli, Lorella, Marchetti, Piero, Dotta, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979342/ https://www.ncbi.nlm.nih.gov/pubmed/29649109 http://dx.doi.org/10.3390/ijms19041170

Ejemplares similares

MicroRNAs as Regulators of Insulin Signaling: Research Updates and Potential Therapeutic Perspectives in Type 2 Diabetes
por: Nigi, Laura, et al.
Publicado: (2018)

Targeting microRNAs as a Therapeutic Strategy to Reduce Oxidative Stress in Diabetes
por: Grieco, Giuseppina Emanuela, et al.
Publicado: (2019)

The Landscape of microRNAs in βCell: Between Phenotype Maintenance and Protection
por: Grieco, Giuseppina Emanuela, et al.
Publicado: (2021)

MicroRNAs: Novel Players in the Dialogue between Pancreatic Islets and Immune System in Autoimmune Diabetes
por: Ventriglia, Giuliana, et al.
Publicado: (2015)

Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors
por: Nigi, Laura, et al.
Publicado: (2022)

Circulating microRNA (miRNA) Expression Profiling in Plasma of Patients with Gestational Diabetes Mellitus Reveals Upregulation of miRNA miR-330-3p
por: Sebastiani, Guido, et al.
Publicado: (2017)

Circulating microRNAs Signature for Predicting Response to GLP1-RA Therapy in Type 2 Diabetic Patients: A Pilot Study
por: Formichi, Caterina, et al.
Publicado: (2021)

MicroRNA Expression in the Aqueous Humor of Patients with Diabetic Macular Edema
por: Grieco, Giuseppina Emanuela, et al.
Publicado: (2020)

The microRNA and the perspectives of miR-302
por: Chen, Emily Yen Yu, et al.
Publicado: (2019)

Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation
por: Grieco, Giuseppina E., et al.
Publicado: (2022)

Application of the microRNA‐302/367 cluster in cancer therapy
por: Liu, Jiajia, et al.
Publicado: (2020)

Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression
por: Sebastiani, Guido, et al.
Publicado: (2017)

Comprehensive serum and tissue microRNA profiling in dedifferentiated liposarcoma
por: Kohama, Isaku, et al.
Publicado: (2021)

Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes
por: Nigi, Laura, et al.
Publicado: (2020)

Circulating MicroRNAs as Biomarkers of Gestational Diabetes Mellitus: Updates and Perspectives
por: Guarino, Elisa, et al.
Publicado: (2018)

c-Jun-mediated microRNA-302d-3p induces RPE dedifferentiation by targeting p21(Waf1/Cip1)
por: Jiang, Chao, et al.
Publicado: (2018)

Circulating microRNA, secreted microRNA and exogenous plant microRNA
por: Zhang, Chenyu
Publicado: (2012)

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells
por: Parr, Callum J. C., et al.
Publicado: (2016)

SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature
por: Fignani, Daniela, et al.
Publicado: (2020)

MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells
por: Judson, Robert L, et al.
Publicado: (2013)

Protocol to analyze circulating small non-coding RNAs by high-throughput RNA sequencing from human plasma samples
por: Grieco, Giuseppina E., et al.
Publicado: (2021)

Non-Coding RNAs: Novel Players in Insulin Resistance and Related Diseases
por: Formichi, Caterina, et al.
Publicado: (2021)

Extracellular Vesicles in Immune System Regulation and Type 1 Diabetes: Cell-to-Cell Communication Mediators, Disease Biomarkers, and Promising Therapeutic Tools
por: Grieco, Giuseppina Emanuela, et al.
Publicado: (2021)

Down-regulation of miR-302b, an ESC-specific microRNA, in Gastric Adenocarcinoma
por: Khalili, Mitra, et al.
Publicado: (2012)

MicroRNA-302a Suppresses Tumor Cell Proliferation by Inhibiting AKT in Prostate Cancer
por: Zhang, Gui-Ming, et al.
Publicado: (2015)

MicroRNA biogenesis and activity in plant cell dedifferentiation stimulated by cell wall removal
por: Dełeńko, Konrad, et al.
Publicado: (2022)

The Expression of microRNA and microRNA Clusters in the Aging Heart
por: Zhang, Xiaomin, et al.
Publicado: (2012)

Rapid Generation of MicroRNA Sponges for MicroRNA Inhibition
por: Kluiver, Joost, et al.
Publicado: (2012)

Pre-microRNA and Mature microRNA in Human Mitochondria
por: Barrey, Eric, et al.
Publicado: (2011)

Organ donor pancreases for the study of human islet cell histology and pathophysiology: a precious and valuable resource
por: Marchetti, Piero, et al.
Publicado: (2018)

Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
por: Fioravanti, Antonella, et al.
Publicado: (2020)

MicroRNA-302a Functions as a Putative Tumor Suppressor in Colon Cancer by Targeting Akt
por: Sun, Shengjie, et al.
Publicado: (2014)

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion
por: Ye, Ying, et al.
Publicado: (2018)

Correction: MicroRNA-302a Suppresses Tumor Cell Proliferation by Inhibiting AKT in Prostate Cancer
Publicado: (2020)

Inflammation-Mediated Regulation of MicroRNA Expression in Transplanted Pancreatic Islets
por: Bravo-Egana, Valia, et al.
Publicado: (2012)

MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets
por: Klein, Dagmar, et al.
Publicado: (2013)

MicroRNA Regulation of Cholesterol Metabolism
por: Rotllan, Noemi, et al.
Publicado: (2012)

Circulating plasma microRNA-126, microRNA-145, and microRNA-155 and their association with atherosclerotic plaque characteristics
por: Knoka, Evija, et al.
Publicado: (2020)

MicroRNA-503 and the Extended MicroRNA-16 Family in Angiogenesis
por: Caporali, Andrea, et al.
Publicado: (2011)

Modulation of microRNA Activity by Semi-microRNAs
por: Plante, Isabelle, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o7auu99jvqobjb42ige6ijspnr