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Resistance to Anti-Angiogenic Therapy in Cancer—Alterations to Anti-VEGF Pathway
Anti-angiogenic therapy is one of the promising strategies for many types of solid cancers. Bevacizumab (Avastin), a recombinant humanized monoclonal antibody of vascular endothelial growth factor (VEGF) A, was approved for the first time as an anti-angiogenic drug for the treatment of metastatic co...
Autores principales: | Itatani, Yoshiro, Kawada, Kenji, Yamamoto, Takamasa, Sakai, Yoshiharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979390/ https://www.ncbi.nlm.nih.gov/pubmed/29670046 http://dx.doi.org/10.3390/ijms19041232 |
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