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Hyperinsulinemia Promotes Esophageal Cancer Development in a Surgically-Induced Duodeno-Esophageal Reflux Murine Model

Hyperinsulinemia could have a role in the growing incidence of esophageal adenocarcinoma (EAC) and its pre-cancerous lesion, Barrett’s Esophagus, a possible consequence of Gastro-Esophageal Reflux Disease. Obesity is known to mediate esophageal carcinogenesis through different mechanisms including i...

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Detalles Bibliográficos
Autores principales:	Arcidiacono, Diletta, Dedja, Arben, Giacometti, Cinzia, Fassan, Matteo, Nucci, Daniele, Francia, Simona, Fabris, Federico, Zaramella, Alice, Gallagher, Emily J., Cassaro, Mauro, Rugge, Massimo, LeRoith, Derek, Alberti, Alfredo, Realdon, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979452/ https://www.ncbi.nlm.nih.gov/pubmed/29662006 http://dx.doi.org/10.3390/ijms19041198

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