Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2

Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although VEGF-A ligands bind to both VEGFR1 and VEGFR2, they primarily signal via VEGFR2 leading to endothelial cell proliferation,...

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Detalles Bibliográficos
Autores principales: Peach, Chloe J., Mignone, Viviane W., Arruda, Maria Augusta, Alcobia, Diana C., Hill, Stephen J., Kilpatrick, Laura E., Woolard, Jeanette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979509/
https://www.ncbi.nlm.nih.gov/pubmed/29690653
http://dx.doi.org/10.3390/ijms19041264

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