Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications

Maintenance of atrial fibrillation is a complex mechanism, including extensive electrical and structural remodeling of the atria which involves progressive fibrogenesis. Galectin-3 is a biomarker of fibrosis, and, thus, may be involved in atrial remodeling in atrial fibrillation patients. We review...

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Autores principales: Clementy, Nicolas, Piver, Eric, Bisson, Arnaud, Andre, Clémentine, Bernard, Anne, Pierre, Bertrand, Fauchier, Laurent, Babuty, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979515/
https://www.ncbi.nlm.nih.gov/pubmed/29587379
http://dx.doi.org/10.3390/ijms19040976
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author Clementy, Nicolas
Piver, Eric
Bisson, Arnaud
Andre, Clémentine
Bernard, Anne
Pierre, Bertrand
Fauchier, Laurent
Babuty, Dominique
author_facet Clementy, Nicolas
Piver, Eric
Bisson, Arnaud
Andre, Clémentine
Bernard, Anne
Pierre, Bertrand
Fauchier, Laurent
Babuty, Dominique
author_sort Clementy, Nicolas
collection PubMed
description Maintenance of atrial fibrillation is a complex mechanism, including extensive electrical and structural remodeling of the atria which involves progressive fibrogenesis. Galectin-3 is a biomarker of fibrosis, and, thus, may be involved in atrial remodeling in atrial fibrillation patients. We review the role of galectin-3 in AF mechanisms and its potential therapeutic implications.
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spelling pubmed-59795152018-06-10 Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications Clementy, Nicolas Piver, Eric Bisson, Arnaud Andre, Clémentine Bernard, Anne Pierre, Bertrand Fauchier, Laurent Babuty, Dominique Int J Mol Sci Review Maintenance of atrial fibrillation is a complex mechanism, including extensive electrical and structural remodeling of the atria which involves progressive fibrogenesis. Galectin-3 is a biomarker of fibrosis, and, thus, may be involved in atrial remodeling in atrial fibrillation patients. We review the role of galectin-3 in AF mechanisms and its potential therapeutic implications. MDPI 2018-03-25 /pmc/articles/PMC5979515/ /pubmed/29587379 http://dx.doi.org/10.3390/ijms19040976 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Clementy, Nicolas
Piver, Eric
Bisson, Arnaud
Andre, Clémentine
Bernard, Anne
Pierre, Bertrand
Fauchier, Laurent
Babuty, Dominique
Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications
title Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications
title_full Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications
title_fullStr Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications
title_full_unstemmed Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications
title_short Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications
title_sort galectin-3 in atrial fibrillation: mechanisms and therapeutic implications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979515/
https://www.ncbi.nlm.nih.gov/pubmed/29587379
http://dx.doi.org/10.3390/ijms19040976
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