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Baicalein Rescues Delayed Cooling via Preservation of Akt Activation and Akt-Mediated Phospholamban Phosphorylation

Cooling reduces the ischemia/reperfusion (I/R) injury seen in sudden cardiac arrest (SCA) by decreasing the burst of reactive oxygen species (ROS). Its cardioprotection is diminished when delay in reaching the target temperature occurs. Baicalein, a flavonoid derived from the root of Scutellaria bai...

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Detalles Bibliográficos
Autores principales: Shao, Zuohui, Chen, Sy-Jou, Zhu, Xiangdong, Lee, Chunpei, Huang, Hsien-Hao, Meliton, Angelo, Li, Changqing, Vanden Hoek, Terry L., Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979521/
https://www.ncbi.nlm.nih.gov/pubmed/29587364
http://dx.doi.org/10.3390/ijms19040973

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