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Baicalein Rescues Delayed Cooling via Preservation of Akt Activation and Akt-Mediated Phospholamban Phosphorylation
Cooling reduces the ischemia/reperfusion (I/R) injury seen in sudden cardiac arrest (SCA) by decreasing the burst of reactive oxygen species (ROS). Its cardioprotection is diminished when delay in reaching the target temperature occurs. Baicalein, a flavonoid derived from the root of Scutellaria bai...
Autores principales: | Shao, Zuohui, Chen, Sy-Jou, Zhu, Xiangdong, Lee, Chunpei, Huang, Hsien-Hao, Meliton, Angelo, Li, Changqing, Vanden Hoek, Terry L., Li, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979521/ https://www.ncbi.nlm.nih.gov/pubmed/29587364 http://dx.doi.org/10.3390/ijms19040973 |
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