Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases

The CDKN1C gene encodes the p57(Kip2) protein which has been identified as the third member of the CIP/Kip family, also including p27(Kip1) and p21(Cip1). In analogy with these proteins, p57(Kip2) is able to bind tightly and inhibit cyclin/cyclin-dependent kinase complexes and, in turn, modulate cel...

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Detalles Bibliográficos
Autores principales: Stampone, Emanuela, Caldarelli, Ilaria, Zullo, Alberto, Bencivenga, Debora, Mancini, Francesco Paolo, Della Ragione, Fulvio, Borriello, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979523/
https://www.ncbi.nlm.nih.gov/pubmed/29614816
http://dx.doi.org/10.3390/ijms19041055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979523/
https://www.ncbi.nlm.nih.gov/pubmed/29614816
http://dx.doi.org/10.3390/ijms19041055

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