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Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases
The CDKN1C gene encodes the p57(Kip2) protein which has been identified as the third member of the CIP/Kip family, also including p27(Kip1) and p21(Cip1). In analogy with these proteins, p57(Kip2) is able to bind tightly and inhibit cyclin/cyclin-dependent kinase complexes and, in turn, modulate cel...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979523/ https://www.ncbi.nlm.nih.gov/pubmed/29614816 http://dx.doi.org/10.3390/ijms19041055 |