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Oncosuppressors and Oncogenes: Role in Haemangioma Genesis and Potential for Therapeutic Targeting
Genetic lesions in proto-oncogenes result in the perturbation of angiogenesis, the formation of neovessels from a pre-existing microvasculature. Similarly, the subversion of tumor suppressor genes promotes tumor vascularization. Excessive neovessel formation is associated with various neoplasms such...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979526/ https://www.ncbi.nlm.nih.gov/pubmed/29652858 http://dx.doi.org/10.3390/ijms19041192 |