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Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog
The over two dozen CYP2B structures of human, rabbit, and woodrat enzymes solved in the last decade have significantly enhanced our understanding of the structure-function relationships of drug metabolizing enzymes. More recently, an important role has emerged for halogen-π interactions in the CYP2B...
Autores principales: | Shah, Manish B., Zhang, Qinghai, Halpert, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979536/ https://www.ncbi.nlm.nih.gov/pubmed/29596329 http://dx.doi.org/10.3390/ijms19041025 |
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