Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes

The key lipid metabolism transcription factor sterol regulatory element-binding protein (SREBP)-1a integrates gene regulatory effects of hormones, cytokines, nutrition and metabolites as lipids, glucose, or cholesterol via phosphorylation by different mitogen activated protein kinase (MAPK) cascades...

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Detalles Bibliográficos
Autores principales: Knebel, Birgit, Hartwig, Sonja, Jacob, Sylvia, Kettel, Ulrike, Schiller, Martina, Passlack, Waltraud, Koellmer, Cornelia, Lehr, Stefan, Müller-Wieland, Dirk, Kotzka, Jorg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979561/
https://www.ncbi.nlm.nih.gov/pubmed/29587401
http://dx.doi.org/10.3390/ijms19040980

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