Cargando…

EP4 as a Therapeutic Target for Aggressive Human Breast Cancer

G-protein-coupled receptors (GPCRs, also called seven-transmembrane or heptahelical receptors) are a superfamily of cell surface receptor proteins that bind to many extracellular ligands and transmit signals to an intracellular guanine nucleotide-binding protein (G-protein). When a ligand binds, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Majumder, Mousumi, Nandi, Pinki, Omar, Ahmed, Ugwuagbo, Kingsley Chukwunonso, Lala, Peeyush K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979567/ https://www.ncbi.nlm.nih.gov/pubmed/29596308 http://dx.doi.org/10.3390/ijms19041019

Ejemplares similares

Pri-miR526b and Pri-miR655 Are Potential Blood Biomarkers for Breast Cancer
por: Majumder, Mousumi, et al.
Publicado: (2021)

PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells
por: Nandi, Pinki, et al.
Publicado: (2017)

Prostaglandin E2 Receptor 4 (EP4) as a Therapeutic Target to Impede Breast Cancer-Associated Angiogenesis and Lymphangiogenesis
por: De Paz Linares, Guillermo Antonio, et al.
Publicado: (2021)

Mir526b and Mir655 Promote Tumour Associated Angiogenesis and Lymphangiogenesis in Breast Cancer
por: Hunter, Stephanie, et al.
Publicado: (2019)

Prostaglandin E2 promotes embryonic vascular development and maturation in zebrafish
por: Ugwuagbo, Kingsley Chukwunonso, et al.
Publicado: (2019)

miR526b and miR655 Induce Oxidative Stress in Breast Cancer
por: Shin, Bonita, et al.
Publicado: (2019)

Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions
por: Majumder, Mousumi, et al.
Publicado: (2014)

The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis
por: Tutunea-Fatan, Elena, et al.
Publicado: (2015)

Human trophoblast stem cell self-renewal and differentiation: Role of decorin
por: Nandi, Pinki, et al.
Publicado: (2018)

COX-2 induces oncogenic micro RNA miR655 in human breast cancer
por: Majumder, Mousumi, et al.
Publicado: (2018)

Decorin–induced, preeclampsia-associated microRNA-512-3p restrains extravillous trophoblast functions by targeting USF2/PPP3R1 axis
por: Halari, Chidambra D., et al.
Publicado: (2022)

Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells
por: Tordjman, Joshua, et al.
Publicado: (2019)

Co-Expression of α9β1 Integrin and VEGF-D Confers Lymphatic Metastatic Ability to a Human Breast Cancer Cell Line MDA-MB-468LN
por: Majumder, Mousumi, et al.
Publicado: (2012)

Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties
por: Kundu, Namita, et al.
Publicado: (2013)

Nuclear Ep-ICD accumulation predicts aggressive clinical course in early stage breast cancer patients
por: Srivastava, Gunjan, et al.
Publicado: (2014)

Phospho-TCTP as a therapeutic target of dihydroartemisinin for aggressive breast cancer cells
por: Lucibello, Maria, et al.
Publicado: (2015)

DOT1L: a new therapeutic target for aggressive breast cancer
por: Lee, Jeong-Yeon, et al.
Publicado: (2015)

Editorial: Cellular and molecular determinants of pregnancy success at the fetal-maternal interface in health and disease
por: Lala, Peeyush K., et al.
Publicado: (2023)

Diagnostic and therapeutic agents that target alpha-synuclein in Parkinson’s disease
por: Nwabufo, Chukwunonso K., et al.
Publicado: (2022)

ON AGGRESSION
por: Nandi, D.N.
Publicado: (1985)

Editorial: Immunometabolism and therapeutic targeting of aggressive cancers
por: Ždralević, Maša, et al.
Publicado: (2023)

Roles of Two Small Leucine-Rich Proteoglycans Decorin and Biglycan in Pregnancy and Pregnancy-Associated Diseases
por: Halari, Chidambra D., et al.
Publicado: (2021)

Applying Metabolomics to Understand the Aggressive Phenotype and Identify Novel Therapeutic Targets in Glioblastoma
por: Ahmed, Kamran A., et al.
Publicado: (2014)

Racial Disparity in Quadruple Negative Breast Cancer: Aggressive Biology and Potential Therapeutic Targeting and Prevention
por: Jinna, Nikita, et al.
Publicado: (2022)

EP(4) receptor as a new target for bronchodilator therapy
por: Buckley, James, et al.
Publicado: (2011)

An Ep-ICD Based Index Is a Marker of Aggressiveness and Poor Prognosis in Thyroid Carcinoma
por: He, Helen C.-H., et al.
Publicado: (2012)

Relevance of BCAR4 in tamoxifen resistance and tumour aggressiveness of human breast cancer
por: Godinho, M F E, et al.
Publicado: (2010)

Vascular patterns provide therapeutic targets in aggressive neuroblastic tumors
por: Tadeo, Irene, et al.
Publicado: (2016)

EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis
por: Ralhan, Ranju, et al.
Publicado: (2010)

Novel high–throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP(2) and EP(4) receptors
por: Sieber, Patrick, et al.
Publicado: (2018)

Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells
por: Nandi, Pinki, et al.
Publicado: (2021)

Inhibitory effects of prostaglandin EP(4 )receptors on human eosinophils
por: Luschnig-Schratl, Petra, et al.
Publicado: (2009)

Exosomes as Theranostic Targets: Implications for the Clinical Prognosis of Aggressive Cancers
por: Gulati, Richa, et al.
Publicado: (2022)

Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
por: Conery, Andrew R, et al.
Publicado: (2016)

Effects of EpCAM overexpression on human breast cancer cell lines
por: Gostner, Johanna M, et al.
Publicado: (2011)

Prostaglandin E2 promotes human CD34(+) cells homing through EP2 and EP4 in vitro
por: Wang, Yaqun, et al.
Publicado: (2017)

Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E(2) Activation in Human Podocytes
por: Mangelsen, Eva, et al.
Publicado: (2020)

Functional expression of human prostaglandin E2 receptor 4 (EP4) in E. coli and characterization of the binding property of EP4 with G(α) proteins
por: Kim, Nam Hyuk, et al.
Publicado: (2020)

Opposing effects of prostaglandin E(2) receptors EP3 and EP4 on mouse and human β-cell survival and proliferation
por: Carboneau, Bethany A., et al.
Publicado: (2017)

Correction: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
por: Conery, Andrew R, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bi58h8hactlaucjfdvo3vlp5ii