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Demyelination in Multiple Sclerosis: Reprogramming Energy Metabolism and Potential PPARγ Agonist Treatment Approaches
Demyelination in multiple sclerosis (MS) cells is the site of several energy metabolic abnormalities driven by dysregulation between the opposed interplay of peroxisome proliferator-activated receptor γ (PPARγ) and WNT/β-catenin pathways. We focus our review on the opposing interactions observed in...
Autores principales: | Vallée, Alexandre, Lecarpentier, Yves, Guillevin, Rémy, Vallée, Jean-Noël |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979570/ https://www.ncbi.nlm.nih.gov/pubmed/29659554 http://dx.doi.org/10.3390/ijms19041212 |
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