Cargando…

Hypoxia induces endothelial-mesenchymal transition in pulmonary vascular remodeling

It is well established that hypoxia induces epithelial-mesenchymal transition in vitro and in vivo. However, the role of hypoxia in endothelial-mesenchymal transition (EndMT), an important process in the pathogenesis of pulmonary hypertension, is not well-characterized. The present study demonstrate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Bo, Niu, Wen, Dong, Hai-Ying, Liu, Man-Ling, Luo, Ying, Li, Zhi-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979824/ https://www.ncbi.nlm.nih.gov/pubmed/29568878 http://dx.doi.org/10.3892/ijmm.2018.3584

Ejemplares similares

Reversal of Hypoxic Pulmonary Hypertension by Hypoxia-Inducible Overexpression of Angiotensin-(1-7) in Pulmonary Endothelial Cells
por: Liu, Man-Ling, et al.
Publicado: (2020)

Endothelial to Mesenchymal Transition in Pulmonary Vascular Diseases
por: Yun, Eunsik, et al.
Publicado: (2020)

Endothelial-to-mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis
por: Gaikwad, Archana Vijay, et al.
Publicado: (2023)

Vascular Remodelling and Mesenchymal Transition in Systemic Sclerosis
por: Nicolosi, Pier Andrea, et al.
Publicado: (2016)

Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition
por: Gaikwad, Archana Vijay, et al.
Publicado: (2022)

Activation of Nrf2 Attenuates Pulmonary Vascular Remodeling via Inhibiting Endothelial-to-Mesenchymal Transition: an Insight from a Plant Polyphenol
por: Chen, Yucai, et al.
Publicado: (2017)

Hypoxia Upregulates NOTCH3 Signaling Pathway to Promote Endothelial-Mesenchymal Transition in Pulmonary Artery Endothelial Cells
por: Wang, Li-Le, et al.
Publicado: (2021)

Tanshinone IIA Inhibits Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation via Akt/Skp2/p27-Associated Pathway
por: Luo, Ying, et al.
Publicado: (2013)

Mesenchymal stromal cell-derived exosomes improve pulmonary hypertension through inhibition of pulmonary vascular remodeling
por: Zhang, Shanshan, et al.
Publicado: (2020)

Endothelial-to-Mesenchymal Transition, Vascular Inflammation, and Atherosclerosis
por: Chen, Pei-Yu, et al.
Publicado: (2020)

Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition
por: Yu, Min, et al.
Publicado: (2020)

Endothelial senescence mediates hypoxia-induced vascular remodeling by modulating PDGFB expression
por: Kyi, Priscilla, et al.
Publicado: (2022)

Benefits of Curcumin in the Vasculature: A Therapeutic Candidate for Vascular Remodeling in Arterial Hypertension and Pulmonary Arterial Hypertension?
por: Li, Ke-Xue, et al.
Publicado: (2022)

Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species–Mediated Mitochondrial Dysfunction
por: Chen, Jian, et al.
Publicado: (2017)

Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial‐mesenchymal transition in salivary adenoid cystic carcinoma
por: Wang, Hao‐fan, et al.
Publicado: (2019)

Shinjulactone A Blocks Vascular Inflammation and the Endothelial-Mesenchymal Transition
por: Jang, Ye-eun, et al.
Publicado: (2022)

Macrophage-derived foam cells impair endothelial barrier function by inducing endothelial-mesenchymal transition via CCL-4
por: Yang, Ying, et al.
Publicado: (2017)

Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary fibrosis and vascular obliteration?
por: Eapen, Mathew Suji, et al.
Publicado: (2020)

MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells
por: Zhu, Kai, et al.
Publicado: (2014)

Upregulation of MicroRNA-214 Contributes to the Development of Vascular Remodeling in Hypoxia-induced Pulmonary Hypertension Via Targeting CCNL2
por: Liu, HaiTao, et al.
Publicado: (2016)

Iron oxide nanoparticles induce reversible endothelial-to-mesenchymal transition in vascular endothelial cells at acutely non-cytotoxic concentrations
por: Wen, Tao, et al.
Publicado: (2019)

The alveolar epithelial cells are involved in pulmonary vascular remodeling and constriction of hypoxic pulmonary hypertension
por: Wang, Yanxia, et al.
Publicado: (2021)

IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1α and VEGF Expression in Vascular Endothelial Cells
por: Liu, Jie, et al.
Publicado: (2018)

RUNX3 modulates hypoxia-induced endothelial-to-mesenchymal transition of human cardiac microvascular endothelial cells
por: Liu, Yanhua, et al.
Publicado: (2017)

Endogenous Estrogen Attenuates Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Vasoconstriction and Pulmonary Arterial Smooth Muscle Cells Proliferation
por: Xu, Dunquan, et al.
Publicado: (2013)

Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
por: Paddenberg, Renate, et al.
Publicado: (2007)

Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema
por: Howard, L. S., et al.
Publicado: (2012)

Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension
por: Li, Tangzhiming, et al.
Publicado: (2019)

Nanoparticle endothelial delivery of PGC-1α attenuates hypoxia-induced pulmonary hypertension by attenuating EndoMT-caused vascular wall remodeling
por: Cai, Dunpeng, et al.
Publicado: (2022)

Mechanism of Hypoxia-Mediated Smooth Muscle Cell Proliferation Leading to Vascular Remodeling
por: Huang, Xiaojuan, et al.
Publicado: (2022)

Natural reversal of pulmonary vascular remodeling and right ventricular remodeling in SU5416/hypoxia-treated Sprague-Dawley rats
por: Zungu-Edmondson, Makhosazane, et al.
Publicado: (2017)

Role of Endothelial to Mesenchymal Transition in the Pathogenesis of the Vascular Alterations in Systemic Sclerosis
por: Jimenez, Sergio A.
Publicado: (2013)

Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2(Akita/+) Mice
por: Guihard, Pierre J., et al.
Publicado: (2016)

MicroRNAs as critical regulators of the endothelial to mesenchymal transition in vascular biology
por: Kim, Jongmin
Publicado: (2018)

The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension
por: Karoor, Vijaya, et al.
Publicado: (2021)

Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats
por: Yu, Lunyin, et al.
Publicado: (2011)

Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in rats
por: Li, Xian-Wei, et al.
Publicado: (2015)

Effects of FHL1 and P21 on hypoxia-induced pulmonary vascular remodeling in neonatal rats
por: Du, Yanna, et al.
Publicado: (2017)

Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamics
por: Chen, Xi, et al.
Publicado: (2019)

Astragaloside IV attenuates hypoxia-induced pulmonary vascular remodeling via the Notch signaling pathway
por: Yao, Jiamei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_euel8c6kr13g6mr67krci4ngsg