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Deregulation of microRNA-31a-5p is involved in the development of primary hypertension by suppressing apoptosis of pulmonary artery smooth muscle cells via targeting TP53

The present study aimed to identify the association between microRNA (miRNA/miR)-31a-5p and the development of hypertension, and its potential molecular mechanism. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blot analyses were performed to validate the candidat...

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Detalles Bibliográficos
Autores principales: Feng, Qiang, Tian, Tao, Liu, Junfeng, Zhang, Li, Qi, Jiangang, Lin, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979825/
https://www.ncbi.nlm.nih.gov/pubmed/29620173
http://dx.doi.org/10.3892/ijmm.2018.3597