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Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes

Epidermal barrier function is provided by the highly keratinised stratum corneum and also by tight junctions (TJs) in the granular layer of skin. The development of the TJ barrier significantly deteriorates in response to ultraviolet B radiation (UVB). Following exposure to UVB, keratinocytes accumu...

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Detalles Bibliográficos
Autores principales: El-Chami, Cécile, Haslam, Iain S., Steward, Martin C., O’Neill, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979960/
https://www.ncbi.nlm.nih.gov/pubmed/29581434
http://dx.doi.org/10.1038/s41598-018-22533-0