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Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes
Epidermal barrier function is provided by the highly keratinised stratum corneum and also by tight junctions (TJs) in the granular layer of skin. The development of the TJ barrier significantly deteriorates in response to ultraviolet B radiation (UVB). Following exposure to UVB, keratinocytes accumu...
Autores principales: | El-Chami, Cécile, Haslam, Iain S., Steward, Martin C., O’Neill, Catherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979960/ https://www.ncbi.nlm.nih.gov/pubmed/29581434 http://dx.doi.org/10.1038/s41598-018-22533-0 |
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