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Droplet digital polymerase chain reaction assay and peptide nucleic acid‐locked nucleic acid clamp method for RHOA mutation detection in angioimmunoblastic T‐cell lymphoma

Angioimmunoblastic T‐cell lymphoma (AITL) is a subtype of nodal peripheral T‐cell lymphoma (PTCL). Somatic RHOA mutations, most frequently found at the hotspot site c.50G > T, p.Gly17Val (G17V RHOA mutation) are a genetic hallmark of AITL. Detection of the G17V RHOA mutations assists prompt and a...

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Detalles Bibliográficos
Autores principales: Tanzima Nuhat, Sharna, Sakata‐Yanagimoto, Mamiko, Komori, Daisuke, Hattori, Keiichiro, Suehara, Yasuhito, Fukumoto, Kota, Fujisawa, Manabu, Kusakabe, Manabu, Matsue, Kosei, Wakamatsu, Hirotake, Shimadzu, Mitsunobu, Chiba, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980118/
https://www.ncbi.nlm.nih.gov/pubmed/29493850
http://dx.doi.org/10.1111/cas.13557