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P21‐activated kinase 2 is essential in maintenance of peripheral Foxp3(+) regulatory T cells

The p21‐activated kinase 2 (Pak2), an effector molecule of the Rho family GTPases Rac and Cdc42, regulates diverse functions of T cells. Previously, we showed that Pak2 is required for development and maturation of T cells in the thymus, including thymus‐derived regulatory T (Treg) cells. However, w...

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Detalles Bibliográficos
Autores principales: Choi, Jinyong, Pease, David Randall, Chen, Siqi, Zhang, Bin, Phee, Hyewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980155/
https://www.ncbi.nlm.nih.gov/pubmed/29297928
http://dx.doi.org/10.1111/imm.12886