Inhibition of yes‐associated protein down‐regulates PD‐L1 (CD274) expression in human malignant pleural mesothelioma

Although tumour PD‐L1 (CD274) expression had been used as a predictive biomarker in checkpoint immunotherapy targeting the PD1/PD‐L1 axis in various cancers, the regulation of PD‐L1 (CD274) expression is unclear. Yes‐associated protein (YAP), an important oncogenic protein in Hippo signalling pathwa...

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Detalles Bibliográficos
Autores principales: Hsu, Ping‐Chih, Miao, Jinbai, Wang, Yu‐Cheng, Zhang, Wen‐Qian, Yang, Yi‐Lin, Wang, Chih‐Wei, Yang, Cheng‐Ta, Huang, Zhen, You, Joanna, Xu, Zhidong, Jablons, David M., You, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980156/
https://www.ncbi.nlm.nih.gov/pubmed/29575535
http://dx.doi.org/10.1111/jcmm.13593

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