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Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial
Bio‐Strath(®) is a plasmolyzed yeast product enriched with herbs, malt, honey and orange juice. In this study, the effect of Equi‐Strath(®), the adapted product for horses, on the equine immune system was evaluated. A routine influenza booster vaccination was used as a model to study the effects of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980167/ https://www.ncbi.nlm.nih.gov/pubmed/29851307 http://dx.doi.org/10.1002/vms3.95 |
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author | van Dorland, Hendrika A. Zanoni, Reto Gerber, Vinzenz Jeannerat, Elise Wiederkehr, Danja Burger, Dominik |
author_facet | van Dorland, Hendrika A. Zanoni, Reto Gerber, Vinzenz Jeannerat, Elise Wiederkehr, Danja Burger, Dominik |
author_sort | van Dorland, Hendrika A. |
collection | PubMed |
description | Bio‐Strath(®) is a plasmolyzed yeast product enriched with herbs, malt, honey and orange juice. In this study, the effect of Equi‐Strath(®), the adapted product for horses, on the equine immune system was evaluated. A routine influenza booster vaccination was used as a model to study the effects of Equi‐Strath(®) supplementation on the immune response. Twenty healthy Franches‐Montagnes stallions with pre‐existing antibody levels were randomly divided into a study group (SG, n = 10) receiving 0.06 mL/kg bodyweight of Equi‐Strath(®), and a control group (CG, n = 10), receiving the same amount of placebo, daily. The supplement and placebo were given from week 1 until week 14 of the trial. After 10 weeks, the horses were vaccinated with a commercial vaccine containing equine influenza strains of the H3N8 subtype. Antibody titres in blood were measured at day 0 before vaccination, and 14 and 32 days after vaccination. In addition, a complete blood count (CBC) was performed on day 0 and day 32. A linear increase of haemagglutination inhibition titres in both groups was observed after vaccination, but with no difference between treatment groups. CBC components remained unaffected by treatment. In conclusion, daily Equi‐Strath(®) supplementation did not affect the adaptive immune response in stallions after a routine commercial H3N8 influenza booster vaccination. |
format | Online Article Text |
id | pubmed-5980167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-59801672018-06-06 Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial van Dorland, Hendrika A. Zanoni, Reto Gerber, Vinzenz Jeannerat, Elise Wiederkehr, Danja Burger, Dominik Vet Med Sci Original Articles Bio‐Strath(®) is a plasmolyzed yeast product enriched with herbs, malt, honey and orange juice. In this study, the effect of Equi‐Strath(®), the adapted product for horses, on the equine immune system was evaluated. A routine influenza booster vaccination was used as a model to study the effects of Equi‐Strath(®) supplementation on the immune response. Twenty healthy Franches‐Montagnes stallions with pre‐existing antibody levels were randomly divided into a study group (SG, n = 10) receiving 0.06 mL/kg bodyweight of Equi‐Strath(®), and a control group (CG, n = 10), receiving the same amount of placebo, daily. The supplement and placebo were given from week 1 until week 14 of the trial. After 10 weeks, the horses were vaccinated with a commercial vaccine containing equine influenza strains of the H3N8 subtype. Antibody titres in blood were measured at day 0 before vaccination, and 14 and 32 days after vaccination. In addition, a complete blood count (CBC) was performed on day 0 and day 32. A linear increase of haemagglutination inhibition titres in both groups was observed after vaccination, but with no difference between treatment groups. CBC components remained unaffected by treatment. In conclusion, daily Equi‐Strath(®) supplementation did not affect the adaptive immune response in stallions after a routine commercial H3N8 influenza booster vaccination. John Wiley and Sons Inc. 2018-02-27 /pmc/articles/PMC5980167/ /pubmed/29851307 http://dx.doi.org/10.1002/vms3.95 Text en © 2018 The Authors. Veterinary Medicine and Science Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles van Dorland, Hendrika A. Zanoni, Reto Gerber, Vinzenz Jeannerat, Elise Wiederkehr, Danja Burger, Dominik Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial |
title | Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial |
title_full | Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial |
title_fullStr | Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial |
title_full_unstemmed | Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial |
title_short | Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath(®): a randomized trial |
title_sort | antibody response to influenza booster vaccination in franches‐montagnes stallions supplemented with equi‐strath(®): a randomized trial |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980167/ https://www.ncbi.nlm.nih.gov/pubmed/29851307 http://dx.doi.org/10.1002/vms3.95 |
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