Cargando…

c‐Src inhibitor selectively inhibits triple‐negative breast cancer overexpressed Vimentin in vitro and in vivo

Oncogene c‐Src has been found to be a potential target for the treatment of triple‐negative breast cancer (TNBC). However, the therapeutic effects of the c‐Src inhibitor on TNBC patients are controversial compared to those on cell lines. The molecular mechanisms of the inhibitory effects of the c‐Sr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lou, Longquan, Yu, Ziyi, Wang, Yue, Wang, Shui, Zhao, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980174/ https://www.ncbi.nlm.nih.gov/pubmed/29575318 http://dx.doi.org/10.1111/cas.13572

Ejemplares similares

Vimentin Promotes the Aggressiveness of Triple Negative Breast Cancer Cells Surviving Chemotherapeutic Treatment
por: Winter, Marie, et al.
Publicado: (2021)

Dasatinib inhibits c-src phosphorylation and prevents the proliferation of Triple-Negative Breast Cancer (TNBC) cells which overexpress Syndecan-Binding Protein (SDCBP)
por: Qian, Xiao-Long, et al.
Publicado: (2017)

Overexpressions of Vimentin and Integrins in Human Metastatic Spine Tumors
por: Park, Sung Bae, et al.
Publicado: (2015)

Anti-Vimentin Nanobody Decreases Glioblastoma Cell Invasion In Vitro and In Vivo
por: Zottel, Alja, et al.
Publicado: (2023)

Cyr61 as mediator of Src signaling in triple negative breast cancer cells
por: Sánchez-Bailón, María Pilar, et al.
Publicado: (2015)

Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration
por: Yang, Cheng-Yi, et al.
Publicado: (2019)

Overexpression of the vimentin gene in transgenic mice inhibits normal lens cell differentiation
Publicado: (1989)

Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer
por: Liu, Zhaoyun, et al.
Publicado: (2017)

Triple-negative vimentin-positive heterogeneous feline mammary carcinomas as a potential comparative model for breast cancer
por: Caliari, Diego, et al.
Publicado: (2014)

Correction: Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration
por: Yang, Cheng-Yi, et al.
Publicado: (2019)

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
por: Fan, Fan, et al.
Publicado: (2023)

Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo
por: Stedt, Hanna, et al.
Publicado: (2012)

Correlation Between Intensity of Vimentin Immuno-expression in Young Women with Triple Negative Breast Cancer and Its Cliniocopathological Parameters
por: Lumongga, Fitriani, et al.
Publicado: (2022)

Prognostic Value of Vimentin in Triple Negative Breast Cancer Patients Depends on Chemotherapy Regimen and p53 Mutant Expression
por: Purwanto, Ibnu, et al.
Publicado: (2023)

Tissue Inhibitor of Metalloproteinases-1 Overexpression Mediates Chemoresistance in Triple-Negative Breast Cancer Cells
por: Agnello, Lisa, et al.
Publicado: (2023)

Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer
por: Kohale, Ishwar N., et al.
Publicado: (2022)

The Relevance of the SH2 Domain for c-Src Functionality in Triple-Negative Breast Cancer Cells
por: Mayoral-Varo, Víctor, et al.
Publicado: (2021)

Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells
Publicado: (1990)

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers
por: Pang, Kyoungwha, et al.
Publicado: (2019)

MMP-1 is overexpressed in triple-negative breast cancer tissues and the knockdown of MMP-1 expression inhibits tumor cell malignant behaviors in vitro
por: Wang, Qi-Min, et al.
Publicado: (2019)

Nanoparticles Loaded with the BET Inhibitor JQ1 Block the Growth of Triple Negative Breast Cancer Cells In Vitro and In Vivo
por: Maggisano, Valentina, et al.
Publicado: (2019)

Fibroblast growth factor 18 promotes the growth, migration and invasion of MDA-MB-231 cells
por: Yu, Ziyi, et al.
Publicado: (2018)

In vitro antineoplastic activity in triple-negative breast cancer cell line and in vivo
por: Madeira, Klesia, et al.
Publicado: (2014)

Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo
por: Jeon, Hyein, et al.
Publicado: (2016)

Vimentin and Anti Vimentin Antibodies in Chagas' Disease
por: Nascimento, Marilda Savoia, et al.
Publicado: (2018)

Sauropus brevipes ethanol extract negatively regulates inflammatory responses in vivo and in vitro by targeting Src, Syk and IRAK1
por: Kim, Ji Hye, et al.
Publicado: (2021)

The Effect of Chemoradiotherapy with SRC Tyrosine Kinase Inhibitor, PP2 and Temozolomide on Malignant Glioma Cells In Vitro and In Vivo
por: Eom, Keun-Yong, et al.
Publicado: (2016)

Suppressing Src-Mediated EGFR Signaling by Sustained Calcium Supply Targeting Triple-Negative Breast Cancer
por: Jeong, Keun-Yeong, et al.
Publicado: (2023)

The potential of Src inhibitors
por: Elias, Daniel, et al.
Publicado: (2015)

ATG9A Is Overexpressed in Triple Negative Breast Cancer and Its In Vitro Extinction Leads to the Inhibition of Pro-Cancer Phenotypes
por: Claude-Taupin, Aurore, et al.
Publicado: (2018)

Aquaporin 1 knockdown inhibits triple-negative breast cancer cell proliferation and invasion in vitro and in vivo
por: Ji, Yinan, et al.
Publicado: (2021)

Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies
por: Lahat, Guy, et al.
Publicado: (2010)

Overexpression of β-Arrestins inhibits proliferation and motility in triple negative breast cancer cells
por: Bostanabad, Saber Yari, et al.
Publicado: (2021)

Selection and Characterization of Vimentin-Binding Aptamer Motifs for Ovarian Cancer
por: Costello, Andrea M., et al.
Publicado: (2021)

Overexpression of miRNA-3613-3p Enhances the Sensitivity of Triple Negative Breast Cancer to CDK4/6 Inhibitor Palbociclib
por: Yu, Yuanhang, et al.
Publicado: (2020)

Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo
por: Park, See-Hyoung, et al.
Publicado: (2016)

The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
por: Brzozowa, Marlena, et al.
Publicado: (2015)

Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer
por: Canonici, Alexandra, et al.
Publicado: (2020)

Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells
por: Lin, Wanjun, et al.
Publicado: (2017)

Src Inhibition Can Synergize with Gemcitabine and Reverse Resistance in Triple Negative Breast Cancer Cells via the AKT/c-Jun Pathway
por: Wu, Zhen-Hua, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6sc8ll4jkdvq4hc1nf9bt47vb1