Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration

Spermidine has therapeutic effects in many diseases including as heart diastolic function, myopathic defects and neurodegenerative disorders via autophagy activation. Autophagy has been found to mitigate cell apoptosis in intervertebral disc degeneration (IDD). Accordingly, we theorize that spermidi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Zengming, Wang, Zhou‐Guang, Chen, Yu, Chen, Jian, Khor, Sinan, Li, Jiawei, He, Zili, Wang, Qingqing, Zhang, Hongyu, Xu, Ke, Fanghua, Gong, Xiao, Jian, Wang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980193/
https://www.ncbi.nlm.nih.gov/pubmed/29575654
http://dx.doi.org/10.1111/jcmm.13586

Ejemplares similares

Ejemplares similares