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Tim‐3 blockade promotes iNKT cell function to inhibit HBV replication

Increased expression of T cell immunoglobulin and mucin domain‐3 (Tim‐3) on invariant natural killer T (iNKT) cells is reported in chronic hepatitis B virus (HBV) infection. However, whether Tim‐3 regulates iNKT cells in chronic HBV condition remains unclear. In this study, our results showed that t...

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Detalles Bibliográficos
Autores principales: Xu, Yong, Wang, Zehua, Du, Xianhong, Liu, Yuan, Song, Xiaojia, Wang, Tixiao, Tan, Siyu, Liang, Xiaohong, Gao, Lifen, Ma, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980221/
https://www.ncbi.nlm.nih.gov/pubmed/29602251
http://dx.doi.org/10.1111/jcmm.13600