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Podoplanin: An emerging cancer biomarker and therapeutic target
Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on transformed cells, cancer associated fibroblasts and inflammatory macrophages that contribute to cancer progression. In particular, PDPN increases tumor cell clonal capacity, epithelial mesenchymal transition, migratio...
Autores principales: | Krishnan, Harini, Rayes, Julie, Miyashita, Tomoyuki, Ishii, Genichiro, Retzbach, Edward P., Sheehan, Stephanie A., Takemoto, Ai, Chang, Yao‐Wen, Yoneda, Kazue, Asai, Jun, Jensen, Lasse, Chalise, Lushun, Natsume, Atsushi, Goldberg, Gary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980289/ https://www.ncbi.nlm.nih.gov/pubmed/29575529 http://dx.doi.org/10.1111/cas.13580 |
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