Cargando…

Novel method for DNA methylation analysis using high‐performance liquid chromatography and its clinical application

The aim of this study was to develop a new methodology that is suitable for DNA methylation diagnostics and to demonstrate its clinical applicability. We developed a new anion‐exchange column for high‐performance liquid chromatography (HPLC) with electrostatic and hydrophobic properties. Both cytosi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yotani, Takuya, Yamada, Yuriko, Arai, Eri, Tian, Ying, Gotoh, Masahiro, Komiyama, Motokiyo, Fujimoto, Hiroyuki, Sakamoto, Michiie, Kanai, Yae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980336/ https://www.ncbi.nlm.nih.gov/pubmed/29520901 http://dx.doi.org/10.1111/cas.13566

Ejemplares similares

Prognostication of patients with clear cell renal cell carcinomas based on quantification of DNA methylation levels of CpG island methylator phenotype marker genes
por: Tian, Ying, et al.
Publicado: (2014)

Establishment of diagnostic criteria for upper urinary tract urothelial carcinoma based on genome-wide DNA methylation analysis
por: Fujimoto, Mao, et al.
Publicado: (2020)

Alterations of the spindle checkpoint pathway in clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas
por: Arai, Eri, et al.
Publicado: (2015)

Quantification of DNA methylation for carcinogenic risk estimation in patients with non-alcoholic steatohepatitis
por: Kuramoto, Junko, et al.
Publicado: (2022)

Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas
por: Arai, Eri, et al.
Publicado: (2012)

Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling
por: Endo, Yutaka, et al.
Publicado: (2021)

DNA methylation status of the SPHK1 and LTB genes underlies the clinicopathological diversity of non-alcoholic steatohepatitis-related hepatocellular carcinomas
por: Tsuda, Noboru, et al.
Publicado: (2022)

Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis
por: Kanai, Yae, et al.
Publicado: (1996)

Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome
por: Yamanoi, Kazuhiro, et al.
Publicado: (2015)

DNA methyltransferase 3B expression is associated with poor outcome of stage I testicular seminoma
por: Arai, Eri, et al.
Publicado: (2012)

Comprehensive Exploration of Novel Chimeric Transcripts in Clear Cell Renal Cell Carcinomas Using Whole Transcriptome Analysis
por: Gotoh, Masahiro, et al.
Publicado: (2014)

Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas
por: Tian, Ying, et al.
Publicado: (2020)

Copy number alterations in urothelial carcinomas: their clinicopathological significance and correlation with DNA methylation alterations
por: Nishiyama, Naotaka, et al.
Publicado: (2011)

Diagnosis and Prognostication of Ductal Adenocarcinomas of the Pancreas Based on Genome-Wide DNA Methylation Profiling by Bacterial Artificial Chromosome Array-Based Methylated CpG Island Amplification
por: Gotoh, Masahiro, et al.
Publicado: (2011)

Increased DNA Methyltransferase Expression Is Associated with an Early Stage of Human Hepatocarcinogenesis
por: Sun, Lin, et al.
Publicado: (1997)

Prognostication of early-onset endometrioid endometrial cancer based on genome-wide DNA methylation profiles
por: Hirano, Takuro, et al.
Publicado: (2022)

Genome-wide DNA methylation profiles in both precancerous conditions and clear cell renal cell carcinomas are correlated with malignant potential and patient outcome
por: Arai, Eri, et al.
Publicado: (2009)

Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome
por: Arai, Eri, et al.
Publicado: (2014)

Assessment of MGMT methylation status using high-performance liquid chromatography in newly diagnosed glioblastoma
por: Hanihara, Mitsuto, et al.
Publicado: (2020)

DNA Methylation Profiles at Precancerous Stages Associated with Recurrence of Lung Adenocarcinoma
por: Sato, Takashi, et al.
Publicado: (2013)

β‐Catenin Accumulation and Mutation of Exon 3 of the β‐Catenin Gene in Hepatocellular Carcinoma
por: Kondo, Yutaka, et al.
Publicado: (1999)

Multilayer-omics analyses of human cancers: exploration of biomarkers and drug targets based on the activities of the International Human Epigenome Consortium
por: Kanai, Yae, et al.
Publicado: (2014)

Tolerability and Efficacy of Neoadjuvant Chemotherapy with a Tri-Weekly Interval Methotrexate, Doxorubicin, Vinblastine, and Cisplatin Regimen for Patients with Locally Advanced Bladder Cancer
por: Arai, Satoko, et al.
Publicado: (2018)

Diagnostic markers of urothelial cancer based on DNA methylation analysis
por: Chihara, Yoshitomo, et al.
Publicado: (2013)

Neoadjuvant crizotinib in ALK-rearranged inflammatory myofibroblastic tumor of the urinary bladder: A case report
por: Nagumo, Yoshiyuki, et al.
Publicado: (2018)

DNA hypermethylation of the ZNF132 gene participates in the clinicopathological aggressiveness of ‘pan-negative’-type lung adenocarcinomas
por: Hamada, Kenichi, et al.
Publicado: (2020)

Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma
por: Saito, Kosuke, et al.
Publicado: (2016)

Epigenetic clustering of lung adenocarcinomas based on DNA methylation profiles in adjacent lung tissue: Its correlation with smoking history and chronic obstructive pulmonary disease
por: Sato, Takashi, et al.
Publicado: (2014)

Genome-wide DNA methylation profile of early-onset endometrial cancer: its correlation with genetic aberrations and comparison with late-onset endometrial cancer
por: Makabe, Takeshi, et al.
Publicado: (2019)

Characterization of High‐Molecular‐Mass Forms of Basic Fibroblast Growth Factor Produced by Hepatocellular Carcinoma Cells: Possible Involvement of Basic Fibroblast Growth Factor in Hepatocarcinogenesis
por: Shimoyama, Yutaka, et al.
Publicado: (1991)

Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes
por: Marumo, Takeshi, et al.
Publicado: (2020)

Evaluation of clinical formalin‐fixed paraffin‐embedded tissue quality for targeted‐bisulfite sequencing
por: Ohmomo, Hideki, et al.
Publicado: (2020)

Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related carcinogenesis
por: Kuramoto, Junko, et al.
Publicado: (2017)

Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: a single-institutional methylome analysis using 1007 tissue specimens
por: Ohara, Kentaro, et al.
Publicado: (2017)

Cytoreductive robot‐assisted prostatectomy for systemic prostate rhabdomyosarcoma presenting as urinary retention
por: Kirisawa, Takahiro, et al.
Publicado: (2021)

Effect of storage conditions on salivary polyamines quantified via liquid chromatography-mass spectrometry
por: Tomita, Atsumi, et al.
Publicado: (2018)

Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL
por: Watanabe, Atsushi, et al.
Publicado: (2023)

Cooperative participation of epigenomic and genomic alterations in the clinicopathological diversity of gastric adenocarcinomas: significance of cell adhesion and epithelial–mesenchymal transition-related signaling pathways
por: Yang, Menghan, et al.
Publicado: (2020)

Preparative liquid chromatography /
Publicado: (1987)

Liquid column chromatography
Publicado: (1985)

Cannot write session to /tmp/vufind_sessions/sess_1t3o4hi2ki9k1dmstd3v7igdid