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Hispidulin suppresses cell growth and metastasis by targeting PIM1 through JAK2/STAT3 signaling in colorectal cancer
Colorectal cancer (CRC) accounts for over 600 000 deaths annually worldwide. The current study aims to evaluate the value of proto‐oncogene PIM1 as a therapeutic target in CRC and investigate the anticancer activity of hispidulin, a naturally occurring phenolic flavonoid compound, against CRC. Immun...
Autores principales: | Liu, Kaili, Gao, Hui, Wang, Qiaoyun, Wang, Longyuan, Zhang, Bin, Han, Zhiwu, Chen, Xuehong, Han, Mei, Gao, Mingquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980372/ https://www.ncbi.nlm.nih.gov/pubmed/29575334 http://dx.doi.org/10.1111/cas.13575 |
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