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High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression
High mobility group box 1 (HMGB1) is a non-histone protein localised in the cell nucleus, where it interacts with DNA and promotes nuclear transcription events. HMGB1 levels are elevated during acute myeloid leukaemia (AML) progression followed by participation of this protein in triggering signalli...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980411/ https://www.ncbi.nlm.nih.gov/pubmed/29872582 http://dx.doi.org/10.1080/2162402X.2018.1438109 |