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High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression

High mobility group box 1 (HMGB1) is a non-histone protein localised in the cell nucleus, where it interacts with DNA and promotes nuclear transcription events. HMGB1 levels are elevated during acute myeloid leukaemia (AML) progression followed by participation of this protein in triggering signalli...

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Detalles Bibliográficos
Autores principales: Yasinska, Inna M., Gonçalves Silva, Isabel, Sakhnevych, Svetlana S., Ruegg, Laura, Hussain, Rohanah, Siligardi, Giuliano, Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Raap, Ulrike, Berger, Steffen, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980411/
https://www.ncbi.nlm.nih.gov/pubmed/29872582
http://dx.doi.org/10.1080/2162402X.2018.1438109

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