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Adenoviral vectors transduce alveolar macrophages in lung cancer models

Adenoviral vectors expressing Cre recombinase are commonly used to initiate tumor formation in murine lung cancer models. While these vectors are designed to target genetic recombination to lung epithelial cells, adenoviruses can infect additional cell types that potentially influence tumor developm...

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Detalles Bibliográficos
Autores principales: Tippimanchai, Darinee D., Nolan, Kyle, Poczobutt, Joanna, Verzosa, Gregory, Li, Howard, Scarborough, Hannah, Huang, Jing, Young, Christian, DeGregori, James, Nemenoff, Raphael A., Malkoski, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980415/
https://www.ncbi.nlm.nih.gov/pubmed/29872579
http://dx.doi.org/10.1080/2162402X.2018.1438105