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Immunoassay methods used in clinical studies for the detection of anti‐drug antibodies to adalimumab and infliximab

We examined the assay formats used to detect anti‐drug antibodies (ADA) in clinical studies of the anti‐tumour necrosis factor (TNF) monoclonal antibodies adalimumab and infliximab in chronic inflammatory disease and their potential impact on pharmacokinetic and clinical outcomes. Using findings of...

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Detalles Bibliográficos
Autores principales: Gorovits, B., Baltrukonis, D. J., Bhattacharya, I., Birchler, M. A., Finco, D., Sikkema, D., Vincent, M. S., Lula, S., Marshall, L., Hickling, T. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980437/
https://www.ncbi.nlm.nih.gov/pubmed/29431871
http://dx.doi.org/10.1111/cei.13112