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The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector
Ubiquitination is a post-translational modification that regulates a myriad of cellular processes in eukaryotes(1–4). The conventional ubiquitination cascade culminates in a covalent linkage between the C-terminus of ubiquitin (Ub) and a target protein, most often on a lysine sidechain(1,5). Recent...
Autores principales: | Akturk, Anil, Wasilko, David J., Wu, Xiaochun, Liu, Yao, Zhang, Yong, Qiu, Jiazhang, Luo, Zhao-Qing, Reiter, Katherine H., Brzovic, Peter S., Klevit, Rachel E., Mao, Yuxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980775/ https://www.ncbi.nlm.nih.gov/pubmed/29795346 http://dx.doi.org/10.1038/s41586-018-0147-6 |
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