Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages

A 47-year-old Japanese man was referred to hospital after the detection of a liver tumor. Dynamic computed tomography and gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging were consistent with a diagnosis of hepatocellular carcinoma (HCC). N...

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Autores principales: Endo, Kei, Kuroda, Hidekatsu, Kakisaka, Keisuke, Oikawa, Takayoshi, Sawara, Kei, Ishida, Kazuyuki, Sugai, Tamotsu, Takikawa, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980804/
https://www.ncbi.nlm.nih.gov/pubmed/29279500
http://dx.doi.org/10.2169/internalmedicine.9697-17
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author Endo, Kei
Kuroda, Hidekatsu
Kakisaka, Keisuke
Oikawa, Takayoshi
Sawara, Kei
Ishida, Kazuyuki
Sugai, Tamotsu
Takikawa, Yasuhiro
author_facet Endo, Kei
Kuroda, Hidekatsu
Kakisaka, Keisuke
Oikawa, Takayoshi
Sawara, Kei
Ishida, Kazuyuki
Sugai, Tamotsu
Takikawa, Yasuhiro
author_sort Endo, Kei
collection PubMed
description A 47-year-old Japanese man was referred to hospital after the detection of a liver tumor. Dynamic computed tomography and gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging were consistent with a diagnosis of hepatocellular carcinoma (HCC). No perfusion defect was observed in the post-vascular phase of contrast-enhanced ultrasound (CEUS). Histopathological staining of the tumor cells was positive for antibodies against HMB-45 and cluster of differentiation (CD) 68, confirming the diagnosis of hepatic angiomyolipoma (HAML). These findings indicated the presence of macrophages in HAML. We herein report a case of HAML explain how macrophages that are present within the tumor affect the staining characteristics in the post-vascular phase of CEUS.
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spelling pubmed-59808042018-06-04 Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages Endo, Kei Kuroda, Hidekatsu Kakisaka, Keisuke Oikawa, Takayoshi Sawara, Kei Ishida, Kazuyuki Sugai, Tamotsu Takikawa, Yasuhiro Intern Med Case Report A 47-year-old Japanese man was referred to hospital after the detection of a liver tumor. Dynamic computed tomography and gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging were consistent with a diagnosis of hepatocellular carcinoma (HCC). No perfusion defect was observed in the post-vascular phase of contrast-enhanced ultrasound (CEUS). Histopathological staining of the tumor cells was positive for antibodies against HMB-45 and cluster of differentiation (CD) 68, confirming the diagnosis of hepatic angiomyolipoma (HAML). These findings indicated the presence of macrophages in HAML. We herein report a case of HAML explain how macrophages that are present within the tumor affect the staining characteristics in the post-vascular phase of CEUS. The Japanese Society of Internal Medicine 2017-12-27 2018-05-01 /pmc/articles/PMC5980804/ /pubmed/29279500 http://dx.doi.org/10.2169/internalmedicine.9697-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Endo, Kei
Kuroda, Hidekatsu
Kakisaka, Keisuke
Oikawa, Takayoshi
Sawara, Kei
Ishida, Kazuyuki
Sugai, Tamotsu
Takikawa, Yasuhiro
Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages
title Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages
title_full Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages
title_fullStr Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages
title_full_unstemmed Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages
title_short Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages
title_sort hepatic angiomyolipoma staining in the post-vascular phase of contrast-enhanced ultrasound due to the presence of macrophages
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980804/
https://www.ncbi.nlm.nih.gov/pubmed/29279500
http://dx.doi.org/10.2169/internalmedicine.9697-17
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