Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma

A 50-year-old man with lung adenocarcinoma (c-T1aN2M1b) experienced reddish purpura mainly on the lower legs after receiving 12 cycles of second-line chemotherapy with docetaxel. There was tumor enlargement on computed tomography performed to assess the therapeutic response, so paraneoplastic IgA va...

Descripción completa

Detalles Bibliográficos
Autores principales: Ota, Shuji, Haruyama, Terunobu, Ishihara, Masashi, Natsume, Maika, Fukasawa, Yoko, Sakamoto, Takahiko, Tanzawa, Shigeru, Usui, Ryo, Honda, Takeshi, Ichikawa, Yasuko, Watanabe, Kiyotaka, Sasajima, Yuko, Seki, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980809/
https://www.ncbi.nlm.nih.gov/pubmed/29279496
http://dx.doi.org/10.2169/internalmedicine.9651-17
Descripción
Sumario:A 50-year-old man with lung adenocarcinoma (c-T1aN2M1b) experienced reddish purpura mainly on the lower legs after receiving 12 cycles of second-line chemotherapy with docetaxel. There was tumor enlargement on computed tomography performed to assess the therapeutic response, so paraneoplastic IgA vasculitis was considered. IgA vasculitis was diagnosed based on a biopsy of the skin lesion and histology of an upper gastrointestinal hemorrhagic mucosal erosion. As IgA vasculitis can lead to serious gastrointestinal or systemic complications, IgA vasculitis should be considered as a differential diagnosis for rashes in patients with malignancy.

Ejemplares similares