Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma

A 50-year-old man with lung adenocarcinoma (c-T1aN2M1b) experienced reddish purpura mainly on the lower legs after receiving 12 cycles of second-line chemotherapy with docetaxel. There was tumor enlargement on computed tomography performed to assess the therapeutic response, so paraneoplastic IgA va...

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Autores principales: Ota, Shuji, Haruyama, Terunobu, Ishihara, Masashi, Natsume, Maika, Fukasawa, Yoko, Sakamoto, Takahiko, Tanzawa, Shigeru, Usui, Ryo, Honda, Takeshi, Ichikawa, Yasuko, Watanabe, Kiyotaka, Sasajima, Yuko, Seki, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980809/
https://www.ncbi.nlm.nih.gov/pubmed/29279496
http://dx.doi.org/10.2169/internalmedicine.9651-17
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author Ota, Shuji
Haruyama, Terunobu
Ishihara, Masashi
Natsume, Maika
Fukasawa, Yoko
Sakamoto, Takahiko
Tanzawa, Shigeru
Usui, Ryo
Honda, Takeshi
Ichikawa, Yasuko
Watanabe, Kiyotaka
Sasajima, Yuko
Seki, Nobuhiko
author_facet Ota, Shuji
Haruyama, Terunobu
Ishihara, Masashi
Natsume, Maika
Fukasawa, Yoko
Sakamoto, Takahiko
Tanzawa, Shigeru
Usui, Ryo
Honda, Takeshi
Ichikawa, Yasuko
Watanabe, Kiyotaka
Sasajima, Yuko
Seki, Nobuhiko
author_sort Ota, Shuji
collection PubMed
description A 50-year-old man with lung adenocarcinoma (c-T1aN2M1b) experienced reddish purpura mainly on the lower legs after receiving 12 cycles of second-line chemotherapy with docetaxel. There was tumor enlargement on computed tomography performed to assess the therapeutic response, so paraneoplastic IgA vasculitis was considered. IgA vasculitis was diagnosed based on a biopsy of the skin lesion and histology of an upper gastrointestinal hemorrhagic mucosal erosion. As IgA vasculitis can lead to serious gastrointestinal or systemic complications, IgA vasculitis should be considered as a differential diagnosis for rashes in patients with malignancy.
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spelling pubmed-59808092018-06-04 Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma Ota, Shuji Haruyama, Terunobu Ishihara, Masashi Natsume, Maika Fukasawa, Yoko Sakamoto, Takahiko Tanzawa, Shigeru Usui, Ryo Honda, Takeshi Ichikawa, Yasuko Watanabe, Kiyotaka Sasajima, Yuko Seki, Nobuhiko Intern Med Case Report A 50-year-old man with lung adenocarcinoma (c-T1aN2M1b) experienced reddish purpura mainly on the lower legs after receiving 12 cycles of second-line chemotherapy with docetaxel. There was tumor enlargement on computed tomography performed to assess the therapeutic response, so paraneoplastic IgA vasculitis was considered. IgA vasculitis was diagnosed based on a biopsy of the skin lesion and histology of an upper gastrointestinal hemorrhagic mucosal erosion. As IgA vasculitis can lead to serious gastrointestinal or systemic complications, IgA vasculitis should be considered as a differential diagnosis for rashes in patients with malignancy. The Japanese Society of Internal Medicine 2017-12-27 2018-05-01 /pmc/articles/PMC5980809/ /pubmed/29279496 http://dx.doi.org/10.2169/internalmedicine.9651-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ota, Shuji
Haruyama, Terunobu
Ishihara, Masashi
Natsume, Maika
Fukasawa, Yoko
Sakamoto, Takahiko
Tanzawa, Shigeru
Usui, Ryo
Honda, Takeshi
Ichikawa, Yasuko
Watanabe, Kiyotaka
Sasajima, Yuko
Seki, Nobuhiko
Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma
title Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma
title_full Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma
title_fullStr Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma
title_full_unstemmed Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma
title_short Paraneoplastic IgA Vasculitis in an Adult with Lung Adenocarcinoma
title_sort paraneoplastic iga vasculitis in an adult with lung adenocarcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980809/
https://www.ncbi.nlm.nih.gov/pubmed/29279496
http://dx.doi.org/10.2169/internalmedicine.9651-17
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