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A Germline Mutation in the BRCA1 3’UTR Variant Predicts Susceptibility to Breast Cancer in a Saudi Arabian Population
PURPOSE: The impact of the BRCA1-3’UTR-variant on BRCA1 gene expression and altered responses to external stimuli was previously tested in vitro using a luciferase reporter assay. Its ability to predict breast cancer risk in women was also assessed but the conclusions were inconsistent. The present...
Autores principales: | Mir, Rashid, Javid, Jamsheed, Al Balawi, Ibrahim Abdullah, Alkharsah, Khaled R., Hadi, Maha Abdel, Rahman, Mostafa Abdel, Hamoud, Ebtesam, Al Alawi, Yousef, Al Zahrani, Attiya Bin Mohammad, Abu-Duhier, FM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
West Asia Organization for Cancer Prevention
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980867/ https://www.ncbi.nlm.nih.gov/pubmed/29582646 http://dx.doi.org/10.22034/APJCP.2018.19.3.859 |
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