Detection of Cytochrome P450 Polymorphisms in Breast Cancer Patients May Impact on Tamoxifen Therapy

BACKGROUND: Breast cancer is the most common cancer among women worldwide. Tamoxifen (TAM), a selective estrogen receptor modulator, is widely used in its treatment. TAM is metabolized by cytochrome P450 (CYP450) enzymes, including CYP2D6, CYP3A5 and CYP2C19, whose genetic variations may have clinic...

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Detalles Bibliográficos
Autores principales: Thota, Kanakaiah, Prasad, K, Rao, Mandava V Basaveswara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980918/
https://www.ncbi.nlm.nih.gov/pubmed/29479969
http://dx.doi.org/10.22034/APJCP.2018.19.2.343

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