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Correlation of Expression Levels of Copper Transporter 1 and Thymidylate Synthase with Treatment Outcomes in Patients with Advanced Non-small Cell Lung Cancer Treated with S-1/Carboplatin Doublet Chemotherapy

BACKGROUND: Copper transporter 1 (CTR1) is a critical determinant of the uptake and cytotoxic effect of the platinum drugs carboplatin and cisplatin. Thymidylate synthase (TS) is an enzyme involved in DNA synthesis and is associated with resistance of tumor cells to 5-fluorouracil. We investigated t...

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Detalles Bibliográficos
Autores principales:	Konishi, Maho, Imai, Asuka, Fujii, Masanori, Sugimoto, Keisuke, Katakami, Nobuyuki, Imai, Yukihiro, Kamoshida, Shingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980931/ https://www.ncbi.nlm.nih.gov/pubmed/29479997 http://dx.doi.org/10.22034/APJCP.2018.19.2.435

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