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Interpretation the Hepatotoxicity Based on Pharmacokinetics Investigated Through Oral Administrated Different Extraction Parts of Polygonum multiflorum on Rats
The liver injury induced by Polygonum multiflorum (PM) used for clinical treatment has recently received widespread attention. This study aimed to determine the hepatotoxicity of PM through pharmacokinetics studies. The extract of PM was separated to isolate the anthraquinone fraction, the tannin an...
Autores principales: | Zhang, Miao, Lin, Longfei, Lin, Hongmei, Qu, Changhai, Yan, Lei, Ni, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980962/ https://www.ncbi.nlm.nih.gov/pubmed/29887801 http://dx.doi.org/10.3389/fphar.2018.00505 |
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