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Ligand Screening Systems for Human Glucose Transporters as Tools in Drug Discovery

Hexoses are the major source of energy and carbon skeletons for biosynthetic processes in all kingdoms of life. Their cellular uptake is mediated by specialized transporters, including glucose transporters (GLUT, SLC2 gene family). Malfunction or altered expression pattern of GLUTs in humans is asso...

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Detalles Bibliográficos
Autores principales: Schmidl, Sina, Iancu, Cristina V., Choe, Jun-yong, Oreb, Mislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980966/
https://www.ncbi.nlm.nih.gov/pubmed/29888221
http://dx.doi.org/10.3389/fchem.2018.00183