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Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies

The promyelocytic leukemia (pml) gene product PML is a tumor suppressor localized mainly in the nucleus of mammalian cells. In the cell nucleus, PML seeds the formation of macromolecular multiprotein complexes, known as PML nuclear bodies (PML NBs). While PML NBs have been implicated in many cellula...

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Detalles Bibliográficos
Autores principales: Hoischen, Christian, Monajembashi, Shamci, Weisshart, Klaus, Hemmerich, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980967/
https://www.ncbi.nlm.nih.gov/pubmed/29888200
http://dx.doi.org/10.3389/fonc.2018.00125