Effect of a Point Mutation in mprF on Susceptibility to Daptomycin, Vancomycin, and Oxacillin in an MRSA Clinical Strain

We previously reported the sequential recovery of daptomycin-nonsusceptible MRSA clinical isolates with an L431F substitution in the MprF protein. The aim of the present study is to determine the effect of this mutation by replacing the mprF gene on the chromosome of a daptomycin-susceptible progeni...

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Detalles Bibliográficos
Autores principales: Chen, Feng-Jui, Lauderdale, Tsai-Ling, Lee, Chen-Hsiang, Hsu, Yu-Chieh, Huang, I-Wen, Hsu, Pei-Chi, Yang, Chung-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980971/
https://www.ncbi.nlm.nih.gov/pubmed/29887848
http://dx.doi.org/10.3389/fmicb.2018.01086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980971/
https://www.ncbi.nlm.nih.gov/pubmed/29887848
http://dx.doi.org/10.3389/fmicb.2018.01086

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