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Effect of a Point Mutation in mprF on Susceptibility to Daptomycin, Vancomycin, and Oxacillin in an MRSA Clinical Strain
We previously reported the sequential recovery of daptomycin-nonsusceptible MRSA clinical isolates with an L431F substitution in the MprF protein. The aim of the present study is to determine the effect of this mutation by replacing the mprF gene on the chromosome of a daptomycin-susceptible progeni...
Autores principales: | Chen, Feng-Jui, Lauderdale, Tsai-Ling, Lee, Chen-Hsiang, Hsu, Yu-Chieh, Huang, I-Wen, Hsu, Pei-Chi, Yang, Chung-Shi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980971/ https://www.ncbi.nlm.nih.gov/pubmed/29887848 http://dx.doi.org/10.3389/fmicb.2018.01086 |
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