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Evaluation of hepatic integrin αvβ3 expression in non-alcoholic steatohepatitis (NASH) model mouse by (18)F-FPP-RGD(2) PET

BACKGROUND: Activated hepatic stellate cells (HSCs), which express integrin αvβ3, are a major fibrogenic factor in NASH pathophysiology. (18)F-labeled cyclic arginine-glycine-aspartic acid penta-peptide ((18)F-FPP-RGD(2)) has been used as a PET probe for tumors expressing integrin αvβ3. The aim of t...

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Detalles Bibliográficos
Autores principales:	Rokugawa, Takemi, Konishi, Haruyo, Ito, Miwa, Iimori, Hitoshi, Nagai, Ryohei, Shimosegawa, Eku, Hatazawa, Jun, Abe, Kohji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981157/ https://www.ncbi.nlm.nih.gov/pubmed/29855729 http://dx.doi.org/10.1186/s13550-018-0394-4

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